The Basics

Opioid overdose occurs when an individual stops breathing due to the effects of the drugs.

  • Naloxone (Narcan) reverses the effects of opioids, allowing an individual experiencing an opioid overdose to breathe normally.

  • Naloxone is a prescription medication, but it is not a controlled substance, not addictive and has no potential for abuse. It has been used in hospitals and by EMS for decades.

  • Naloxone does not work for overdoses of benzodiazepines, cocaine, methamphetamine, or alcohol.

  • In a mixed overdose (opioids and benzos, heroin and cocaine, etc), naloxone will help reverse the effects of the opioids, but will not have any effect on other substances present.

  • Naloxone's effects begin in 2-4/3-5 minutes and last for 30-90 minutes.

  • Rescue breathing should be performed until the naloxone takes effect in order to provide oxygen to the vital organs and prevent brain damage. 

  • It is imperative that an individual who has overdosed and was given naloxone be evaluated and monitored in a medical setting (i.e. emergency department) because the overdose can re-occur after the naloxone wears off.

If naloxone is given to someone not experiencing an opiod overdose, there are no adverse effects. ​

Side Effects 

  • When naloxone is given to an individual experiencing an opioid overdose, they will begin breathing normally and may also have symptoms of opioid withdrawal. These include pain, nausea, vomiting, sweating, and anxiety.

  • With the dose of naloxone provided in community settings, individuals very rarely become combative or violent.


NaloxBox is not intended for outdoor use, however, it certainly is the BEST solution for indoor storage ever. 

  • Naloxone must be stored out of direct light. Effective methods include leaving it in its box or storing in a standard orange medication bottle.

  • Naloxone must be kept at room temperature (59-86°F or 15-30°C). It should never be stored in a refrigerator or a vehicle glove box or trunk.

  • If naloxone is stored improperly, it loses its effectiveness. It does not become harmful if administered.


Expanded Access to Naloxone: State laws 

Good Samaritan : State laws 

Using Naloxone to Reverse Opioid Overdose in the Workplace: Information for Employers and Workers

The Bureau of Labor Statistics (BLS) reported that overdose deaths at work from non-medical use of drugs or alcohol increased by at least 38% annually between 2013 and 2016. The 217 workplace overdose deaths reported in 2016 accounted for 4.2% of occupational injury deaths that year, compared with 1.8% in 2013 [BLS 2017]. This large increase in overdose deaths in the workplace (from all drugs) parallels a surge in overall overdose deaths from opioids reported by CDC [2017]. Workplaces that serve the public (i.e. libraries, restaurants, parks) may also have visitors who overdose while onsite.

Anyone at a workplace, including workers, clients, customers, and visitors, is at risk of overdose if they use opioids. Call 911 immediately for any suspected overdose. Overdose without immediate intervention can quickly lead to death. Consider implementing a program to make naloxone available in the workplace. NaloxBox is the solution to increasing the capacity of bystander rescuers to save a colleague or customer. NaloxBoxes can be centrally located and are easily identifiable for individuals looking to help during an overdose situation. 

Frequently Asked Questions

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